Recombination-activating gene
AN INSTANCE OF MACROMOLECULAR COMPLEX IN HOMO SAPIENS WITH REACTOME ID (R-HSA-8865713)
RAG-1; RAG-2; Recombination activity gene; Rag proteins; Rag protein; RAG protein; Recombination activating gene
The recombination-activating genes (RAGs) encode parts of a protein complex that plays important roles in the rearrangement and recombination of the genes encoding immunoglobulin and T cell receptor molecules. There are two recombination-activating genes RAG1 and RAG2, whose cellular expression is restricted to lymphocytes during their developmental stages.